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*This document is like a lab demo—an example Certificate of Analysis (COA) that showcases what a COA looks like but may not match the latest batch in all its glory. Think of it as a chemistry experiment: close, but not quite the final reaction!
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Bulk Quote| precautionary statement codes | P203, P210, P233, P240, P241, P242, P243, P261, P264, P264+P265, P270, P271, P280, P301+P316, P301+P317, P302+P352, P303+P361+P353, P304+P340, P305+P351+P338, P316, P318, P319, P321, P330, P331, P332+P317, P337+P317, P362+P364, P370+P378, P403+P233, P403+P235, P405, and P501 |
| hazard statements |
| hazards summary | 1,2-Dichloroethane, also called ethylene dichloride, is a manufactured chemical that is not found naturally in the environment. It is a clear liquid and has a pleasant smell and sweet taste. The most common use of 1,2-dichloroethane is in the production of vinyl chloride which is used to make a variety of plastic and vinyl products including polyvinyl chloride (PVC) pipes, furniture and automobile upholstery, wall coverings, housewares, and automobile parts. It is also used to as a solvent and is added to leaded gasoline to remove lead.Exposure to low levels of ethylene dichloride can occur from breathing ambient or workplace air. Inhalation of concentrated ethylene dichloride vapor can induce effects on the human nervous system, liver, and kidneys, as well as respiratory distress, cardiac arrhythmia, nausea, and vomiting. Chronic (long-term) inhalation exposure to ethylene dichloride produced effects on the liver and kidneys in animals. No information is available on the reproductive or developmental effects of ethylene dichloride in humans. Decreased fertility and increased embryo mortality have been observed in inhalation studies of rats. Epidemiological studies are not conclusive regarding the carcinogenic effects of ethylene dichloride, due to concomitant exposure to other chemicals. Following treatment by gavage (experimentally placing the chemical in the stomach), several tumor types were induced in rats and mice. EPA has classified ethylene dichloride as a Group B2, probable human carcinogen.Liquid causes first degree burns on short exposure. Can cause nausea and vomiting, narcosis, liver and kidney injury, and death after high inhalation exposure. |
| symptoms | irritation eyes, corneal opacity. central nervous system depression. nausea, vomiting. dermatitis. liver, kidney, cardiovascular system damage. [potential occupational carcinogen]1,2-Dichloroethane exposure causes abdominal pain, coughing, dizziness, drowsiness, headache, nausea, sore throat, diarrhea, unconsciousness, and vomiting, depending on the contact surface and the intensity. Redness of the eyes or skin occurs upon contact. |
| health effects | Breathing or swallowing large amounts of 1,2-dichloroethane can produce nervous system disorders, kidney diseases, or lung effects. This can also lead to heart failure. Skin lesions and benign pulmonary tumors were reported in animals exposed dermally to liquid 1,2-dichloroethane. 1,2-dichloroethane can cause death from cardiac arrhythmia, bronchitis, hemorrhagic gastritis and colitis, hepatocellular damage, renal tubular necrosis and calcification, central nervous system depression, and histological changes in brain tissue after a sufficient single oral dose. |
| carcinogen classification | IARC Carcinogenic Agent: 1,2-Dichloroethane |
| carcinogen classification | IARC Carcinogenic Classes: Group 2B: Possibly carcinogenic to humans |
| carcinogen classification | IARC Monographs: Volume 20: Some Halogenated HydrocarbonsVolume Sup 7: Overall Evaluations of Carcinogenicity: An Updating of IARC Monographs Volumes 1 to 42, 1987; 440 pages; ISBN 92-832-1411-0 Volume 71: Re-evaluation of Some Organic Chemicals, Hydrazine and Hydrogen Peroxide |
| carcinogen classification | default_key: 2B, possibly carcinogenic to humans. |
