| hazard classes and categories | Acute Tox. 4 (100%)Skin Irrit. 2 (36.22%)Eye Dam. 1 (35.98%)Eye Irrit. 2 (63.86%)STOT SE 3 (36.06%)Repr. 1A (40.91%)STOT RE 1 (74.5%)Acute toxicity - category 4Eye irritation - category 2AAcute toxicity (Oral) - Category 4Serious eye damage/eye irritation - Category 2BReproductive toxicity - Category 1A, Additional category: Effects on or via lactationSpecific target organ toxicity - Single exposure - Category 1 (nervous system), Category 3 (respiratory tract irritation)Specific target organ toxicity - Repeated exposure - Category 1 (nervous system, kidney)Hazardous to the aquatic environment (Acute) - Category 2Hazardous to the aquatic environment (Long-term) - Category 2Teratogens |
| precautionary statement codes | P203, P260, P261, P264, P264+P265, P270, P271, P280, P301+P317, P302+P352, P304+P340, P305+P351+P338, P305+P354+P338, P317, P318, P319, P321, P330, P332+P317, P337+P317, P362+P364, P403+P233, P405, and P501 |
| hazards summary | When dissolved in water, it is a strong irritant. A 1% solution is an irritant with a pH of 11.2. It is poorly absorbed through the skin and has a vapor pressure of approximately zero. When used therapeutically, doses higher than 500-1800 mg/day may cause GI symptoms, thyroid dysfunction, muscle cramps, kidney injury, tremors, and convulsions. Persistent neurological symptoms have occurred after accidental or suicidal overdoses. Lithium salts cause developmental toxicity in humans at therapeutic doses (not in the occupational setting) with increased risk for major malformations, particularly cardiac, in the developing fetus. The minimum dietary requirement for lithium is probably less than 25 ug/day, and the average intake is about 100-2600 ug/day. |
