| hazard signal | Danger |
| hazard classes and categories | Flam. Sol. 2 (42.11%)Aquatic Chronic 4 (57.89%)Specific target organ toxicity - Single exposure - Category 1 (nervous system, kidney, articulation of the bone)Specific target organ toxicity - Repeated exposure - Category 1 (nervous system, articulation of the bone, kidney) |
| precautionary statement codes | P210, P240, P241, P273, P280, P370+P378, and P501 |
| hazard statements | H228 (42.11%): Flammable solid [Danger Flammable solids]H413 (57.89%): May cause long lasting harmful effects to aquatic life [Hazardous to the aquatic environment, long-term hazard] |
| hazards summary | Bismuth is a hepatotoxic agent. Ingestion of high doses of bismuth may cause stomatitis, hyperpigmentation of oral mucosa, kidney dysfunction, myoclonus, and encephalopathy. Elemental bismuth is nontoxic. Bismuth salts are toxic after ingestion. In cases of acute poisoning after ingestion, patients suffer abdominal pain and acute renal failure. In cases of chronic poisoning after repeated ingestion of medications containing bismuth, encephalopathy has been reported. Lipid soluble, organic compounds such as bismuth subsalicylate and bismuth subgallate are toxic to the CNS. Water soluble, organic compounds such as bismuth triglycollamate are toxic to the kidneys. Insoluble, inorganic compounds such as bismuth subnitrate and bismuth subcarbonate have minimal toxicity. |
