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Product No: EE5301

Copper, AAS Standard Solution, Cu 1000 µg/mL in 5% HNO₃

Name: Copper, AAS Standard Solution, Cu 1000 µg/mL in 5% HNO₃
Brand: Chempure

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CAS Number

7440-50-8

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IUPAC name	copper
canonical smiles	[Cu]
inchi	InChI=1S/Cu
inchi key	RYGMFSIKBFXOCR-UHFFFAOYSA-N
molecular formula	Cu
synonyms	7440-50-8 Copper Cu Copper powder cuprum
Compound Description	Copper is a metal that occurs naturally throughout the environment, in rocks, soil, water, and air. Copper is an essential element in plants and animals , which means it is necessary for us to live. Therefore, plants and animals must absorb some copper from eating, drinking, and breathing. Copper is used to make many different kinds of products like wire, plumbing pipes, and sheet metal. U.S. pennies made before 1982 are made of copper, while those made after 1982 are only coated with copper. Copper is also combined with other metals to make brass and bronze pipes and faucets. Copper compounds are commonly used in agriculture to treat plant diseases like mildew, for water treatment and, as preservatives for wood, leather, and fabrics. Reddish lustrous malleable odorless metallic solid. Copper atom is a copper group element atom and a metal allergen. It has a role as a micronutrient and an Escherichia coli metabolite. Copper is a transition metal and a trace element in the body. It is important to the function of many enzymes including cytochrome c oxidase, monoamine oxidase and superoxide dismutase. Copper is commonly used in contraceptive intrauterine devices . Copper is a metabolite found in or produced by Escherichia coli . Copper is an essential trace element that is included in some over-the-counter multivitamin and mineral supplements, even though copper deficiency is quite rare and supplementation is rarely needed. The amounts of copper found in typical supplements has not been associated with serum enzyme elevations or with clinically apparent liver injury. However, accidental or intentional copper overdose can cause an acute liver injury and chronic ingestion of excessive amounts of copper can result in copper overload and chronic liver injury. Copper is a natural product found in Artemia salina, Crotalaria prolongata, and Theobroma cacao with data available. Copper is an element with atomic symbol Cu, atomic number 29, and atomic weight 63. Copper is a mineral with formula of Cu. The IMA symbol is Cu. Copper is an essential nutrient to all higher plants and animals. Physiologically, it exists as an ion in the body. In animals, it is found primarily in the bloodstream, as a cofactor in various enzymes, and in copper-based pigments. In the body, copper shifts between the cuprous and cupric forms, though the majority of the body's copper is in the Cu2+ form. The ability of copper to easily accept and donate electrons explains its important role in oxidation-reduction reactions and in scavenging free radicals. Copper is a critical functional component of a number of essential enzymes known as cuproenzymes. For instance, the copper-dependent enzyme, cytochrome c oxidase, plays a critical role in cellular energy production. By catalyzing the reduction of molecular oxygen to water , cytochrome c oxidase generates an electrical gradient used by the mitochondria to create the vital energy-storing molecule, ATP. Another cuproenzyme, lysyl oxidase, is required for the cross-linking of collagen and elastin, which are essential for the formation of strong and flexible connective tissue. Another cuproeznyme, Monoamine oxidase , plays a role in the metabolism of the neurotransmitters norepinephrine, epinephrine, and dopamine. MAO also functions in the degradation of the neurotransmitter serotonin, which is the basis for the use of MAO inhibitors as antidepressants. One of the most important cuproenzymes is Superoxide dismutase . SOD functions as an antioxidant by catalyzing the conversion of superoxide radicals to hydrogen peroxide, which can subsequently be reduced to water by other antioxidant enzymes. Two forms of SOD contain copper: 1) copper/zinc SOD is found within most cells of the body, including red blood cells, and 2) extracellular SOD is a copper-containing enzyme found at high levels in the lungs and low levels in blood plasma. In sufficient amounts, copper can be poisonous or even fatal to organisms. Copper is normally bound to cuproenzymes and is thus only toxic when unsequestered and unmediated. It is believed that zinc and copper compete for absorption in the digestive tract so that a diet that is excessive in one of these minerals may result in a deficiency in the other. An imbalance of zinc and copper status might be involved in human hypertension. A heavy metal trace element with the atomic symbol Cu, atomic number 29, and atomic weight 63.55. See also: Copper Gluconate ; Copper Naphthenate ; Cupric sulfate, basic copper sulfate dibasic ... View More ...

Computed Properties

Molecular Weight:	63.55 g/mol
Hydrogen Bond Donor Count:	0
Hydrogen Bond Acceptor Count:	0
Rotatable Bond Count:	0
Exact Mass:	62.929597 g/mol
Monoisotopic Mass:	62.929597 g/mol
Topological Polar Surface Area:	0 Å²
Heavy Atom Count:	1
Formal Charge:	0
Complexity:	0
Isotope Atom Count:	0
Defined Atom Stereocenter Count:	0
Undefined Atom Stereocenter Count:	0
Defined Bond Stereocenter Count:	0
Undefined Bond Stereocenter Count:	0
Covalently-Bonded Unit Count:	1
Compound Is Canonicalized:	Yes

Related Compounds

Copper

Cupric Cation

Cuprous ion

Copper, isotope of mass 64

Copper, mol. (Cu2)

Copper-63

Copper-65

Copper Cu-62

Copper Cu-60

Copper Cu-67

Copper Cu-61

Dinuclear Copper Ion

Copper Monohydride

Cupric Cu-67 cation

Cupric cation Cu-64

hazard signal	Danger
hazard classes and categories	Acute Tox. 4 (46.94%) Eye Irrit. 2 (16.25%) Acute Tox. 3 (12.94%) Aquatic Acute 1 (91.25%) Aquatic Chronic 1 (39.44%) Aquatic Chronic 2 (47.06%) Aquatic Chronic 3 (14.25%) Skin sensitization - Category 1A Specific target organ toxicity - Single exposure - Category 1 (digestive system), Category 3 (respiratory tract irritation) Specific target organ toxicity - Single exposure - Category 3 (Respiratory tract irritation) Specific target organ toxicity - Repeated exposure - Category 1 (liver) Hazardous to the aquatic environment (Long-term) - Category 4 Aquatic Chronic 2
precautionary statement codes	P261, P264, P264+P265, P270, P271, P273, P280, P301+P317, P304+P340, P305+P351+P338, P316, P321, P330, P337+P317, P391, P403+P233, P405, and P501
hazard statements	H302 (46.94%): Harmful if swallowed [Warning Acute toxicity, oral] H319 (16.25%): Causes serious eye irritation [Warning Serious eye damage/eye irritation] H331 (12.94%): Toxic if inhaled [Danger Acute toxicity, inhalation] H400 (91.25%): Very toxic to aquatic life [Warning Hazardous to the aquatic environment, acute hazard] H410 (39.44%): Very toxic to aquatic life with long lasting effects [Warning Hazardous to the aquatic environment, long-term hazard] H411 (47.06%): Toxic to aquatic life with long lasting effects [Hazardous to the aquatic environment, long-term hazard] H412 (14.25%): Harmful to aquatic life with long lasting effects [Hazardous to the aquatic environment, long-term hazard]
hazards summary	Copper is a metal that occurs naturally throughout the environment, in rocks, soil, water, and air. Copper is an essential element in plants and animals (including humans), which means it is necessary for us to live. Therefore, plants and animals must absorb some copper from eating, drinking, and breathing. Copper is used to make many different kinds of products like wire, plumbing pipes, and sheet metal. U.S. pennies made before 1982 are made of copper, while those made after 1982 are only coated with copper. Copper is also combined with other metals to make brass and bronze pipes and faucets. Copper compounds are commonly used in agriculture to treat plant diseases like mildew, for water treatment and, as preservatives for wood, leather, and fabrics.Copper fumes can cause metal fume fever. Hemolytic anemia has been reported after toxic ingestion. In acidic conditions, metallic copper releases toxic copper ions. Acute copper poisoning can cause liver injury, methemoglobinemia, and hemolytic anemia. Acute renal failure may result, secondary to massive hemoglobinuria. There are two TLVs, one for Copper, fume, as Cu and one for Copper, dusts and mists, as Cu. There is also a MAK for Copper and its inorganic compounds. Copper in drinking water at >4 mg/L can cause gastrointestinal distress. At higher doses, ingested copper salts can cause hemolysis and injury to the liver and kidneys. In high-dose animal studies, excess copper is embryotoxic. Women with Wilson's disease (excess copper) may have infertility and increased spontaneous abortions. See Copper sulfate.

toxicity summary	Excess copper is sequestered within hepatocyte lysosomes, where it is complexed with metallothionein. Copper hepatotoxicity is believed to occur when the lysosomes become saturated and copper accumulates in the nucleus, causing nuclear damage. This damage is possibly a result of oxidative damage, including lipid peroxidation. Copper inhibits the sulfhydryl group enzymes such as glucose-6-phosphate 1-dehydrogenase, glutathione reductase, and paraoxonases, which protect the cell from free oxygen radicals. It also influences gene expression and is a co-factor for oxidative enzymes such as cytochrome C oxidase and lysyl oxidase. In addition, the oxidative stress induced by copper is thought to activate acid sphingomyelinase, which lead to the production of ceramide, an apoptotic signal, as well as cause hemolytic anemia. Copper-induced emesis results from stimulation of the vagus nerve.
symptoms	irritation eyes, nose, pharynx. nasal septum perforation. metallic taste. dermatitis. In Animals: lung, liver, kidney damage. anemiaBreathing high levels of copper can cause irritation of the nose and throat. Acute symptoms of copper poisoning by ingestion include vomiting, hematemesis , hypotension , melena , coma, jaundice , and gastrointestinal distress. Individuals with glucose-6-phosphate deficiency may be at increased risk of hematologic effects of copper. Hemolytic anemia resulting from the treatment of burns with copper compounds is infrequent. Chronic effects of copper exposure can damage the liver and kidneys.
health effects	Copper toxicity, also called copperiedus, refers to the consequences of an excess of copper in the body. Copperiedus can occur from eating acid foods cooked in uncoated copper cookware, or from exposure to excess copper in drinking water or other environmental sources. Very-high doses of copper can damage liver and kidneys, and can even cause death. Copper may induce allergic responses in sensitive individuals.
carcinogen classification	default_key: No indication of carcinogenicity to humans .

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Documentation

Certificate of Analysis

Lot Number

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CAS #

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About this item

IUPAC name	copper
canonical smiles	[Cu]
inchi	InChI=1S/Cu
inchi key	RYGMFSIKBFXOCR-UHFFFAOYSA-N
molecular formula	Cu
synonyms	7440-50-8 Copper Cu Copper powder cuprum
Compound Description	Copper is a metal that occurs naturally throughout the environment, in rocks, soil, water, and air. Copper is an essential element in plants and animals , which means it is necessary for us to live. Therefore, plants and animals must absorb some copper from eating, drinking, and breathing. Copper is used to make many different kinds of products like wire, plumbing pipes, and sheet metal. U.S. pennies made before 1982 are made of copper, while those made after 1982 are only coated with copper. Copper is also combined with other metals to make brass and bronze pipes and faucets. Copper compounds are commonly used in agriculture to treat plant diseases like mildew, for water treatment and, as preservatives for wood, leather, and fabrics. Reddish lustrous malleable odorless metallic solid. Copper atom is a copper group element atom and a metal allergen. It has a role as a micronutrient and an Escherichia coli metabolite. Copper is a transition metal and a trace element in the body. It is important to the function of many enzymes including cytochrome c oxidase, monoamine oxidase and superoxide dismutase. Copper is commonly used in contraceptive intrauterine devices . Copper is a metabolite found in or produced by Escherichia coli . Copper is an essential trace element that is included in some over-the-counter multivitamin and mineral supplements, even though copper deficiency is quite rare and supplementation is rarely needed. The amounts of copper found in typical supplements has not been associated with serum enzyme elevations or with clinically apparent liver injury. However, accidental or intentional copper overdose can cause an acute liver injury and chronic ingestion of excessive amounts of copper can result in copper overload and chronic liver injury. Copper is a natural product found in Artemia salina, Crotalaria prolongata, and Theobroma cacao with data available. Copper is an element with atomic symbol Cu, atomic number 29, and atomic weight 63. Copper is a mineral with formula of Cu. The IMA symbol is Cu. Copper is an essential nutrient to all higher plants and animals. Physiologically, it exists as an ion in the body. In animals, it is found primarily in the bloodstream, as a cofactor in various enzymes, and in copper-based pigments. In the body, copper shifts between the cuprous and cupric forms, though the majority of the body's copper is in the Cu2+ form. The ability of copper to easily accept and donate electrons explains its important role in oxidation-reduction reactions and in scavenging free radicals. Copper is a critical functional component of a number of essential enzymes known as cuproenzymes. For instance, the copper-dependent enzyme, cytochrome c oxidase, plays a critical role in cellular energy production. By catalyzing the reduction of molecular oxygen to water , cytochrome c oxidase generates an electrical gradient used by the mitochondria to create the vital energy-storing molecule, ATP. Another cuproenzyme, lysyl oxidase, is required for the cross-linking of collagen and elastin, which are essential for the formation of strong and flexible connective tissue. Another cuproeznyme, Monoamine oxidase , plays a role in the metabolism of the neurotransmitters norepinephrine, epinephrine, and dopamine. MAO also functions in the degradation of the neurotransmitter serotonin, which is the basis for the use of MAO inhibitors as antidepressants. One of the most important cuproenzymes is Superoxide dismutase . SOD functions as an antioxidant by catalyzing the conversion of superoxide radicals to hydrogen peroxide, which can subsequently be reduced to water by other antioxidant enzymes. Two forms of SOD contain copper: 1) copper/zinc SOD is found within most cells of the body, including red blood cells, and 2) extracellular SOD is a copper-containing enzyme found at high levels in the lungs and low levels in blood plasma. In sufficient amounts, copper can be poisonous or even fatal to organisms. Copper is normally bound to cuproenzymes and is thus only toxic when unsequestered and unmediated. It is believed that zinc and copper compete for absorption in the digestive tract so that a diet that is excessive in one of these minerals may result in a deficiency in the other. An imbalance of zinc and copper status might be involved in human hypertension. A heavy metal trace element with the atomic symbol Cu, atomic number 29, and atomic weight 63.55. See also: Copper Gluconate ; Copper Naphthenate ; Cupric sulfate, basic copper sulfate dibasic ... View More ...

Computed Properties

Molecular Weight:	63.55 g/mol
Hydrogen Bond Donor Count:	0
Hydrogen Bond Acceptor Count:	0
Rotatable Bond Count:	0
Exact Mass:	62.929597 g/mol
Monoisotopic Mass:	62.929597 g/mol
Topological Polar Surface Area:	0 Å²
Heavy Atom Count:	1
Formal Charge:	0
Complexity:	0
Isotope Atom Count:	0
Defined Atom Stereocenter Count:	0
Undefined Atom Stereocenter Count:	0
Defined Bond Stereocenter Count:	0
Undefined Bond Stereocenter Count:	0
Covalently-Bonded Unit Count:	1
Compound Is Canonicalized:	Yes

Related Compounds

Copper

Cupric Cation

Cuprous ion

Copper, isotope of mass 64

Copper, mol. (Cu2)

Copper-63

Copper-65

Copper Cu-62

Copper Cu-60

Copper Cu-67

Copper Cu-61

Dinuclear Copper Ion

Copper Monohydride

Cupric Cu-67 cation

Cupric cation Cu-64

hazard signal	Danger
hazard classes and categories	Acute Tox. 4 (46.94%) Eye Irrit. 2 (16.25%) Acute Tox. 3 (12.94%) Aquatic Acute 1 (91.25%) Aquatic Chronic 1 (39.44%) Aquatic Chronic 2 (47.06%) Aquatic Chronic 3 (14.25%) Skin sensitization - Category 1A Specific target organ toxicity - Single exposure - Category 1 (digestive system), Category 3 (respiratory tract irritation) Specific target organ toxicity - Single exposure - Category 3 (Respiratory tract irritation) Specific target organ toxicity - Repeated exposure - Category 1 (liver) Hazardous to the aquatic environment (Long-term) - Category 4 Aquatic Chronic 2
precautionary statement codes	P261, P264, P264+P265, P270, P271, P273, P280, P301+P317, P304+P340, P305+P351+P338, P316, P321, P330, P337+P317, P391, P403+P233, P405, and P501
hazard statements	H302 (46.94%): Harmful if swallowed [Warning Acute toxicity, oral] H319 (16.25%): Causes serious eye irritation [Warning Serious eye damage/eye irritation] H331 (12.94%): Toxic if inhaled [Danger Acute toxicity, inhalation] H400 (91.25%): Very toxic to aquatic life [Warning Hazardous to the aquatic environment, acute hazard] H410 (39.44%): Very toxic to aquatic life with long lasting effects [Warning Hazardous to the aquatic environment, long-term hazard] H411 (47.06%): Toxic to aquatic life with long lasting effects [Hazardous to the aquatic environment, long-term hazard] H412 (14.25%): Harmful to aquatic life with long lasting effects [Hazardous to the aquatic environment, long-term hazard]
hazards summary	Copper is a metal that occurs naturally throughout the environment, in rocks, soil, water, and air. Copper is an essential element in plants and animals (including humans), which means it is necessary for us to live. Therefore, plants and animals must absorb some copper from eating, drinking, and breathing. Copper is used to make many different kinds of products like wire, plumbing pipes, and sheet metal. U.S. pennies made before 1982 are made of copper, while those made after 1982 are only coated with copper. Copper is also combined with other metals to make brass and bronze pipes and faucets. Copper compounds are commonly used in agriculture to treat plant diseases like mildew, for water treatment and, as preservatives for wood, leather, and fabrics.Copper fumes can cause metal fume fever. Hemolytic anemia has been reported after toxic ingestion. In acidic conditions, metallic copper releases toxic copper ions. Acute copper poisoning can cause liver injury, methemoglobinemia, and hemolytic anemia. Acute renal failure may result, secondary to massive hemoglobinuria. There are two TLVs, one for Copper, fume, as Cu and one for Copper, dusts and mists, as Cu. There is also a MAK for Copper and its inorganic compounds. Copper in drinking water at >4 mg/L can cause gastrointestinal distress. At higher doses, ingested copper salts can cause hemolysis and injury to the liver and kidneys. In high-dose animal studies, excess copper is embryotoxic. Women with Wilson's disease (excess copper) may have infertility and increased spontaneous abortions. See Copper sulfate.

toxicity summary	Excess copper is sequestered within hepatocyte lysosomes, where it is complexed with metallothionein. Copper hepatotoxicity is believed to occur when the lysosomes become saturated and copper accumulates in the nucleus, causing nuclear damage. This damage is possibly a result of oxidative damage, including lipid peroxidation. Copper inhibits the sulfhydryl group enzymes such as glucose-6-phosphate 1-dehydrogenase, glutathione reductase, and paraoxonases, which protect the cell from free oxygen radicals. It also influences gene expression and is a co-factor for oxidative enzymes such as cytochrome C oxidase and lysyl oxidase. In addition, the oxidative stress induced by copper is thought to activate acid sphingomyelinase, which lead to the production of ceramide, an apoptotic signal, as well as cause hemolytic anemia. Copper-induced emesis results from stimulation of the vagus nerve.
symptoms	irritation eyes, nose, pharynx. nasal septum perforation. metallic taste. dermatitis. In Animals: lung, liver, kidney damage. anemiaBreathing high levels of copper can cause irritation of the nose and throat. Acute symptoms of copper poisoning by ingestion include vomiting, hematemesis , hypotension , melena , coma, jaundice , and gastrointestinal distress. Individuals with glucose-6-phosphate deficiency may be at increased risk of hematologic effects of copper. Hemolytic anemia resulting from the treatment of burns with copper compounds is infrequent. Chronic effects of copper exposure can damage the liver and kidneys.
health effects	Copper toxicity, also called copperiedus, refers to the consequences of an excess of copper in the body. Copperiedus can occur from eating acid foods cooked in uncoated copper cookware, or from exposure to excess copper in drinking water or other environmental sources. Very-high doses of copper can damage liver and kidneys, and can even cause death. Copper may induce allergic responses in sensitive individuals.
carcinogen classification	default_key: No indication of carcinogenicity to humans .

Product No: EE5301

Copper, AAS Standard Solution, Cu 1000 µg/mL in 5% HNO₃

Product No: EE5301

About this item

NAME AND IDENTIFIERS

CHEMICAL AND PHYSICAL PROPERTIES

Related Compounds

SAFETY AND HAZARDS

TOXICITY

About this item

Documentation

Certificate of Analysis

Require a Sample Certificate of Analysis (COA) ?

Reviews

Product No: EE5301

About this item

NAME AND IDENTIFIERS

CHEMICAL AND PHYSICAL PROPERTIES

Related Compounds

SAFETY AND HAZARDS

TOXICITY

Require a Sample Certificate of Analysis (COA) ?