| toxicity summary | IDENTIFICATION AND USE: White amorphous, or crystaline powder. It is odorless and tasteless. It is practically insoluble in alcohol, and acetic acid, and soluble in dilute hydrochloric acid, and nitric acid. Slightly soluble in water. It is used in the manufacture of fertilizers, phosphate compounds, manufacture of milk glass, polishing and dental powders, porcelains, pottery, enameling; clarifying sugar syrups; in animal feeds; as noncaking agent; in textile industry. It is used as a stabilizer in plastics; in meat tenderizers; in food as a buffer and used in medical applications as a calcium replenisher. It veterinary medicine it is used as a dietary supplement and an antacid. It is used in the manufacture of luminescent materials. HUMAN EXPOSURE AND TOXICITY: Tricalcium phosphate is not irritating and toxic doses by ingestion would have to be more than 2 g/kg. Skin sensitization is unusual. Aspiration or inhalation could cause chemical pneumonitis. Implantation of material will cause foreign body reaction. Tricalcium phosphate is contraindicated in treatment of hypocalcemia with hyperphosphatemia which may occur in hypoparathyroidism and renal failure. ANIMAL STUDIES: Tricalcium phosphate exhibited no teratogenic effect in developing chicken embryos. |
