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Product No: DT7933

5-Aminolevulinic acid hydrochloride, min.98% (HPLC)

Name: 5-Aminolevulinic acid hydrochloride
Brand: Chempure

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CAS Number

5451-09-2

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IUPAC name	5-amino-4-oxopentanoic acid;hydrochloride
canonical smiles	C(CC(=O)O)C(=O)CN.Cl
inchi	InChI=1S/C5H9NO3.ClH/c6-3-4(7)1-2-5(8)9;/h1-3,6H2,(H,8,9);1H
inchi key	ZLHFONARZHCSET-UHFFFAOYSA-N
molecular formula	C5H10ClNO3
synonyms	5-Aminolevulinic acid hydrochloride 5451-09-2 Aminolevulinic acid hydrochloride 5-Amino-4-oxopentanoic acid hydrochloride Levulan
Compound Description	5-aminolevulinic acid hydrochloride is a hydrochloride that is the monohydrochloride of 5-aminolevulinic acid. It is metabolised to protoporphyrin IX, a photoactive compound which accumulates in the skin. Used in combination with blue light illumination for the treatment of minimally to moderately thick actinic keratosis of the face or scalp. It has a role as an antineoplastic agent, a photosensitizing agent, a dermatologic drug and a prodrug. It contains a 5-ammoniolevulinic acid. Aminolevulinic Acid Hydrochloride is the hydrochloride salt form of aminolevulinic acid, an aminoketone, used for local photosensitizing therapy. Aminolevulinic acid is a metabolic pro-drug that is converted into the photosensitizer protoporphyrin IX , which accumulates intracellularly. Upon exposure to light of appropriate wavelength , PpIX catalyzes oxygen to singlet oxygen, an intracellular toxin, which can further react to form superoxide and hydroxyl radicals. This leads to cellular cytotoxic effects. A compound produced from succinyl-CoA and GLYCINE as an intermediate in heme synthesis. It is used as a PHOTOCHEMOTHERAPY for actinic KERATOSIS. See also: Aminolevulinic Acid .

Computed Properties

Molecular Weight:	167.59 g/mol
Hydrogen Bond Donor Count:	3
Hydrogen Bond Acceptor Count:	4
Rotatable Bond Count:	4
Exact Mass:	167.0349209 g/mol
Monoisotopic Mass:	167.0349209 g/mol
Topological Polar Surface Area:	80.4 Å²
Heavy Atom Count:	10
Formal Charge:	0
Complexity:	121
Isotope Atom Count:	0
Defined Atom Stereocenter Count:	0
Undefined Atom Stereocenter Count:	0
Defined Bond Stereocenter Count:	0
Undefined Bond Stereocenter Count:	0
Covalently-Bonded Unit Count:	2
Compound Is Canonicalized:	Yes

Related Compounds

Aminolevulinic Acid

Aminolevulinic Acid Hydrochloride

5-Azaniumyl-4-oxopentanoate

5-Amino-4-oxopentanoate

5-Ammoniolevulinic acid

5-Amino-4-oxopentanoic acid;hydron;chloride

5-Amino-5-fluoro-4-oxopentanoic acid

CID 9815326

5-Amino-5,5-dideuterio-4-oxopentanoic acid

5-Amino-3,3,5,5-tetradeuterio-4-oxopentanoic acid

5-Amino-3,3-dideuterio-4-oxopentanoic acid

5-Aminolevulinic acid-13C

5-Amino-2,2-dideuterio-4-oxopentanoic acid

5-Amino-2-fluoro-4-oxopentanoic acid

5-amino-4-oxo(113C)pentanoic acid

hazard signal	Warning
hazard classes and categories	Skin Irrit. 2 (100%) Eye Irrit. 2A (100%)
precautionary statement codes	P264, P264+P265, P280, P302+P352, P305+P351+P338, P321, P332+P317, P337+P317, and P362+P364
hazard statements	H315 (100%): Causes skin irritation [Warning Skin corrosion/irritation] H319 (100%): Causes serious eye irritation [Warning Serious eye damage/eye irritation]

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Documentation

Certificate of Analysis

Lot Number

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CAS #

*This document is like a lab demo—an example Certificate of Analysis (COA) that showcases what a COA looks like but may not match the latest batch in all its glory. Think of it as a chemistry experiment: close, but not quite the final reaction!

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About this item

IUPAC name	5-amino-4-oxopentanoic acid;hydrochloride
canonical smiles	C(CC(=O)O)C(=O)CN.Cl
inchi	InChI=1S/C5H9NO3.ClH/c6-3-4(7)1-2-5(8)9;/h1-3,6H2,(H,8,9);1H
inchi key	ZLHFONARZHCSET-UHFFFAOYSA-N
molecular formula	C5H10ClNO3
synonyms	5-Aminolevulinic acid hydrochloride 5451-09-2 Aminolevulinic acid hydrochloride 5-Amino-4-oxopentanoic acid hydrochloride Levulan
Compound Description	5-aminolevulinic acid hydrochloride is a hydrochloride that is the monohydrochloride of 5-aminolevulinic acid. It is metabolised to protoporphyrin IX, a photoactive compound which accumulates in the skin. Used in combination with blue light illumination for the treatment of minimally to moderately thick actinic keratosis of the face or scalp. It has a role as an antineoplastic agent, a photosensitizing agent, a dermatologic drug and a prodrug. It contains a 5-ammoniolevulinic acid. Aminolevulinic Acid Hydrochloride is the hydrochloride salt form of aminolevulinic acid, an aminoketone, used for local photosensitizing therapy. Aminolevulinic acid is a metabolic pro-drug that is converted into the photosensitizer protoporphyrin IX , which accumulates intracellularly. Upon exposure to light of appropriate wavelength , PpIX catalyzes oxygen to singlet oxygen, an intracellular toxin, which can further react to form superoxide and hydroxyl radicals. This leads to cellular cytotoxic effects. A compound produced from succinyl-CoA and GLYCINE as an intermediate in heme synthesis. It is used as a PHOTOCHEMOTHERAPY for actinic KERATOSIS. See also: Aminolevulinic Acid .

Computed Properties

Molecular Weight:	167.59 g/mol
Hydrogen Bond Donor Count:	3
Hydrogen Bond Acceptor Count:	4
Rotatable Bond Count:	4
Exact Mass:	167.0349209 g/mol
Monoisotopic Mass:	167.0349209 g/mol
Topological Polar Surface Area:	80.4 Å²
Heavy Atom Count:	10
Formal Charge:	0
Complexity:	121
Isotope Atom Count:	0
Defined Atom Stereocenter Count:	0
Undefined Atom Stereocenter Count:	0
Defined Bond Stereocenter Count:	0
Undefined Bond Stereocenter Count:	0
Covalently-Bonded Unit Count:	2
Compound Is Canonicalized:	Yes

Related Compounds

Aminolevulinic Acid

Aminolevulinic Acid Hydrochloride

5-Azaniumyl-4-oxopentanoate

5-Amino-4-oxopentanoate

5-Ammoniolevulinic acid

5-Amino-4-oxopentanoic acid;hydron;chloride

5-Amino-5-fluoro-4-oxopentanoic acid

CID 9815326

5-Amino-5,5-dideuterio-4-oxopentanoic acid

5-Amino-3,3,5,5-tetradeuterio-4-oxopentanoic acid

5-Amino-3,3-dideuterio-4-oxopentanoic acid

5-Aminolevulinic acid-13C

5-Amino-2,2-dideuterio-4-oxopentanoic acid

5-Amino-2-fluoro-4-oxopentanoic acid

5-amino-4-oxo(113C)pentanoic acid

hazard signal	Warning
hazard classes and categories	Skin Irrit. 2 (100%) Eye Irrit. 2A (100%)
precautionary statement codes	P264, P264+P265, P280, P302+P352, P305+P351+P338, P321, P332+P317, P337+P317, and P362+P364
hazard statements	H315 (100%): Causes skin irritation [Warning Skin corrosion/irritation] H319 (100%): Causes serious eye irritation [Warning Serious eye damage/eye irritation]

Product No: DT7933

5-Aminolevulinic acid hydrochloride, min.98% (HPLC)

Product No: DT7933

About this item

NAME AND IDENTIFIERS

CHEMICAL AND PHYSICAL PROPERTIES

Related Compounds

SAFETY AND HAZARDS

About this item

Documentation

Certificate of Analysis

Require a Sample Certificate of Analysis (COA) ?

Reviews

Product No: DT7933

About this item

NAME AND IDENTIFIERS

CHEMICAL AND PHYSICAL PROPERTIES

Related Compounds

SAFETY AND HAZARDS

Require a Sample Certificate of Analysis (COA) ?