| IUPAC name | (2S,6R)-2,6-dimethyl-4-[2-methyl-3-[4-(2-methylbutan-2-yl)phenyl]propyl]morpholine;hydrochloride |
| inchi | InChI=1S/C21H35NO.ClH/c1-7-21(5,6)20-10-8-19(9-11-20)12-16(2)13-22-14-17(3)23-18(4)15-22;/h8-11,16-18H,7,12-15H2,1-6H3;1H/t16?,17-,18+; |
| inchi key | XZKWIPVTHGWDCF-KUZYQSSXSA-N |
| molecular formula | C21H36ClNO |
| synonyms | amorolfine hydrochlorideAmorolfine HCl78613-38-4LocerylPekiron |
| Compound Description | Amorolfine hydrochloride is a hydrochloride resulting from the formal reacton of equimolar amounts of hydrogen chloride and amorolfine. An inhibitor of the action of squalene monooxygenase, Delta reductase and D7-D8 isomerase and an antifungal agent, it is used for the topical treatment of fungal nail and skin infections. It has a role as an EC 1.14.13.132 inhibitor, an EC 5.3.3.5 inhibitor and an EC 1.3.1.70 -sterol reductase) inhibitor. It is a hydrochloride and a morpholine antifungal drug. It contains an amorolfine.Amorolfine Hydrochloride is the hyrochloride salt form of amorolfine, a morpholine antifungal agent. Amorolfine inhibits delta-14-reductase and delta-7,8-isomerase, which depletes ergosterol and causes ignosterol to accumulate in the fungal cytoplasmic cell membrane. |
