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*This document is like a lab demo—an example Certificate of Analysis (COA) that showcases what a COA looks like but may not match the latest batch in all its glory. Think of it as a chemistry experiment: close, but not quite the final reaction!
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Bulk Quote| precautionary statement codes | P203, P210, P233, P240, P241, P242, P243, P261, P262, P264, P264+P265, P270, P271, P280, P301+P317, P302+P352, P303+P361+P353, P304+P340, P305+P351+P338, P316, P317, P318, P319, P321, P330, P332+P317, P337+P317, P361+P364, P362+P364, P370+P378, P403+P233, P403+P235, P405, and P501 |
| hazard statements |
| hazards summary | Propylene oxide is used in the production of polyethers (the primary component of polyurethane foams) and propylene glycol. Acute (short-term) exposure of humans and animals to propylene oxide has caused eye and respiratory tract irritation. Dermal contact, even with dilute solutions, has caused skin irritation and necrosis in humans. Propylene oxide is also a mild central nervous system (CNS) depressant in humans. Inflammatory lesions of the nasal cavity, trachea, and lungs and neurological effects have been observed in animals chronically (long-term) exposed to propylene oxide by inhalation. Propylene oxide has been observed to cause tumors at or near the site of administration in rodents, causing forestomach tumors following ingestion via gavage (experimentally placing the chemical in the stomach) and nasal tumors after inhalation exposure. EPA has classified propylene oxide as a Group B2, probable human carcinogen.Liquid causes first degree burns on short exposure. Allergic contact dermatitis reported in a worker swabbing skin with a disinfectant. Can cause CNS depression and severe eye injuries. A respiratory irritant that may cause pulmonary edema. Causes mild CNS depression in animals after inhalation of high concentrations. A nasal carcinogen in rodents at concentrations causing irritation. NOAEL is 50 ppm. Detoxified more rapidly than ethylene oxide, and this is one of the reasons for the lower carcinogenic potency of propylene oxide. A dermal sensitizer. Propylene oxide (UN1280) has warning of explosive polymerization. |
