| IUPAC name | 1,1-dioxo-6-(trifluoromethyl)-3,4-dihydro-2H-1λ6,2,4-benzothiadiazine-7-sulfonamide |
| inchi | InChI=1S/C8H8F3N3O4S2/c9-8(10,11)4-1-5-7(2-6(4)19(12,15)16)20(17,18)14-3-13-5/h1-2,13-14H,3H2,(H2,12,15,16) |
| inchi key | DMDGGSIALPNSEE-UHFFFAOYSA-N |
| molecular formula | C8H8F3N3O4S2 |
| synonyms | hydroflumethiazide135-09-1DiuredeminaGlomerulinRobezon |
| Compound Description | Hydroflumethiazide is a benzothiadiazine consisting of a 3,4-dihydro-HH-1,2,4-benzothiadiazine bicyclic system dioxygenated on sulfur and carrying trifluoromethyl and aminosulfonyl groups at positions 6 and 7 respectively. A diuretic with actions and uses similar to those of hydrochlorothiazide. It has a role as a diuretic and an antihypertensive agent. It is a benzothiadiazine and a thiazide.A thiazide diuretic with actions and uses similar to those of hydrochlorothiazide. Hydroflumethiazide is a Thiazide Diuretic. The physiologic effect of hydroflumethiazide is by means of Increased Diuresis.Hydroflumethiazide is an intermediate-acting benzothiadiazine sulfonamide derivative belonging to the class of the thiazide diuretics.HYDROFLUMETHIAZIDE is a small molecule drug with a maximum clinical trial phase of IV that was first approved in 1959 and is indicated for cardiovascular disease.A thiazide diuretic with actions and uses similar to those of HYDROCHLOROTHIAZIDE. See also: Hydroflumethiazide; reserpine . |