| IUPAC name | 3-hydroxy-3-methylbutanoic acid |
| canonical smiles | CC(C)(CC(=O)O)O |
| inchi | InChI=1S/C5H10O3/c1-5(2,8)3-4(6)7/h8H,3H2,1-2H3,(H,6,7) |
| inchi key | AXFYFNCPONWUHW-UHFFFAOYSA-N |
| molecular formula | C5H10O3 |
| synonyms | beta-Hydroxyisovaleric acid625-08-13-Hydroxy-3-methylbutanoic acid3-Hydroxyisovaleric acid3-Hydroxy-3-methylbutyric acid |
| Compound Description | 3-hydroxyisovaleric acid is a 3-hydroxy monocarboxylic acid that is isovaleric acid substituted at position 3 by a hydroxy group. Used as indicator of biotin deficiency. It has a role as a human metabolite. It is functionally related to a butyric acid and an isovaleric acid. It is a conjugate acid of a 3-hydroxyisovalerate.beta-Hydroxyisovaleric acid is under investigation in clinical trial NCT03018496 .beta-Hydroxyisovaleric acid is a natural product found in Aloe africana, Arabidopsis thaliana, and other organisms with data available.Juven is an orally bioavailable nutritional supplement. Juven contains the amino acids glutamine and arginine in addition to beta-hydroxy-beta-methylbutyrate . This agent may promote muscle protein synthesis and increase muscle mass. 3-Hydroxyisovaleric acid is a normal human metabolite excreted in the urine. Elevated levels of this compound are found in several inherited disorders such as Dihydrolipoamide dehydrogenase Deficiency, 3-Methylcrotonyl-CoA carboxylase 1 deficiency, 3-Hydroxy-3-methylglutaryl-CoA lyase deficiency . . |
