| hazard signal | Warning |
| hazard classes and categories | Carc. 2 (97.78%)Carc. 2 (97.96%)Carc. 2 (97%)Not ClassifiedCarcinogenicity - Category 2Specific target organ toxicity - Repeated exposure - Category 1 (respiratory organs)Hazardous to the aquatic environment (Long-term) - Category 4Serious eye damage/eye irritation - Category 2BSpecific target organ toxicity - Single exposure - Category 3 (Respiratory tract irritation)Specific target organ toxicity - Repeated exposure - Category 1 (Inhalation: lung)Carc. 2 |
| precautionary statement codes | P203, P280, P318, P405, and P501 |
| hazard statements | H351 (97.78%): Suspected of causing cancer [Warning Carcinogenicity] |
| hazards summary | A study of 1,576 workers in the U.S. exposed to TiO2 for more than one year used incidence data from 1956 through 1985. Mortality data was available from the company for the years 1935 through 1983. There was no excess of lung cancer or chronic respiratory disease and no cases of pulmonary fibrosis. Cases of pulmonary fibrosis associated with exposure to TiO2 have been reported, but the reactions may have been caused by silica present as contamination. No listed effects of short-term or long-term exposure. NIOSH has determined that ultrafine TiO2 is a potential occupational carcinogen but that there are insufficient data at this time to classify fine TiO2 as a potential occupational carcinogen. Summary of Epidemiologic Studies: Overall, these studies provide no clear evidence of elevated risks of lung cancer mortality or morbidity among those workers exposed to TiO2 dust. 2021 TLV Basis: lower respiratory tract irritation, pneumoconiosis. See Titanium. See Anatase.Not a skin irritant. NIOSH has determined that ultrafine TiO2 is a potential occupational carcinogen but that there are insufficient data at this time to classify fine TiO2 as a potential occupational carcinogen. Summary of Epidemiologic Studies: Overall, these studies provide no clear evidence of elevated risks of lung cancer mortality or morbidity among those workers exposed to TiO2 dust. A skin and strong eye irritant. Toxic by inhalation. See Titanium dioxide. |
