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*This document is like a lab demo—an example Certificate of Analysis (COA) that showcases what a COA looks like but may not match the latest batch in all its glory. Think of it as a chemistry experiment: close, but not quite the final reaction!
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Bulk Quote| hazards summary | Dimethylformamide is used as an industrial solvent and in the production of fibers, films, and surface coatings. Acute (short-term) exposure to dimethylformamide has been observed to damage the liver in animals and in humans. Symptoms of acute exposure in humans include abdominal pain, nausea, vomiting, jaundice, alcohol intolerance, and rashes. Chronic (long-term) occupational exposure to dimethylformamide by inhalation has resulted in effects on the liver and digestive disturbances in workers. Human studies suggested a possible association between dimethylformamide exposure and testicular cancer, but further studies failed to confirm this relationship. EPA has not classified dimethylformamide with respect to its carcinogenicity.Liquid causes first degree burns on short exposure. Contact dermatitis reported in epoxy resin handler. Also can provoke alcohol-induced flushing. DMF is toxic to the liver. May cause liver injury and jaundice. Animals exposed to single lethal doses have CNS depression, anesthesia, convulsions, and coma. In the list of 15 chemicals classified as potentially fetotoxic even if MAK value observed. Detailed reviews of these data indicate adverse effects on reproductive and teratogenic endpoints, but only at maternal toxicity. See Carcinogenicity of some industrial chemicals, Volume 115. The BEI for Total N-methylformamide (NMF), which represents the sum of N-methylformamide (NMF) and N-(hydroxymethyl)-N-methylformamide (HMMF), is intended to protect almost all workers from liver damage due to exposure to N,N-dimethylformamide (DMF) by all routes of exposure. |
